![]() We searched PubMed for English-language research articles describing the global burden of adolescent and young adult cancers between Jan 1, 2010, and Feb 1, 2021, using the terms “adolescent and young adult or adolescent or young adult or AYA” and “oncology or cancer or neoplasm or tumor or malignancy” and “global or worldwide or international” and “incidence or mortality or morbidity or burden or prevalence or survival”, and identified no additional comprehensive adolescent and young adult global cancer estimate reports. ![]() However, to our knowledge, no previous publication has incorporated the impact of morbidity or done a comparative analysis of cancer within the broader context of the adolescent and young adult disease burden. These publications have begun to raise awareness of adolescents and young adults as a distinctive population within the oncology community globally. ![]() International adolescent and young adult cancer incidence patterns across time have been reported with data from Cancer Incidence in Five Continents reports, and national-level estimates have been reported from select, primarily high-income, countries. Previous work assessing the global burden of adolescent and young adult cancer has focused on incidence and mortality, and has occasionally used a more restrictive age range than presented in this study. Added complexities of cancer in this age group include the potential impact of a cancer diagnosis on starting or caring for their families and careers, access to care, diagnostic delays, and abandonment of therapy-issues that exist globally. Although improvements in survival for children and adults with cancer are reported in high-income countries, less incremental progress has been observed among adolescents and young adults. As adolescents and young adults with cancer are treated by a variety of specialists, their unique epidemiology and clinical care needs are often overlooked. The Lancet Regional Health – Western PacificĪdolescents and young adults with cancer represent a transition population within the cancer continuum between children and older adults.The Lancet Regional Health – Southeast Asia.The Lancet Gastroenterology & Hepatology.
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